a) Application:
Oral, intravenous, subcutaneous, intraperitoneal, inhalation routes. Single and Multiple administration.
b) Blood sampling
i) Jugular vein cannulation
ii) Retro-orbital plexus.
iii) Tail vein.
iv) Overnight sampling
v) Stress-free handling
c) Bioanalytics:
Fast method development, High throughput, HPLC/MS/MS, GC/MS, RIA, Elisa, CE, RT-PCR.
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a) General Toxicity studies. i) Single-dose ii) Maximum tolerated dose iii) Local tolerance iv) Repeated-dose,…
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Detailed efficacy studies with assessment of the associated parameters and Histopathology. Cardiovascular: MI/ Arrhythmias, Angina,…
Pre-clinical lead optimization is the early assessment of a compound’s development potential. Lead optimization reduces…