The absence of pyrogens in injectable drugs is an indispensable safety control because contaminants causing…
a) Application: Oral, intravenous, subcutaneous, intraperitoneal, inhalation routes. Single and Multiple administration. b) Blood sampling…
a) General Toxicity studies. i) Single-dose ii) Maximum tolerated dose iii) Local tolerance iv) Repeated-dose,…
Detailed efficacy studies with assessment of the associated parameters and Histopathology. Cardiovascular: MI/ Arrhythmias, Angina,…
Pre-clinical lead optimization is the early assessment of a compound’s development potential. Lead optimization reduces…