Abnormal toxicity & Pyrogen testing

5 years ago
Pavan P

The absence of pyrogens in injectable drugs is an indispensable safety control because contaminants causing fever to pose a life-threatening…

Pharmacokinetics and bio analytics.

5 years ago

a) Application: Oral, intravenous, subcutaneous, intraperitoneal, inhalation routes. Single and Multiple administration. b) Blood sampling i) Jugular vein cannulation ii)…

Toxicity studies.

5 years ago

a) General Toxicity studies. i) Single-dose ii) Maximum tolerated dose iii) Local tolerance iv) Repeated-dose, 2, 4, 13, 26, 39…

Exploratory Toxicity Studies

5 years ago

MTD Acute/Sub-Acute Tox 7/14D DRF 28D Tox Acute Dermal Tox Genotoxicity Mucous Membrane Irritation Local Tolerance

Efficacy studies.

5 years ago

Detailed efficacy studies with assessment of the associated parameters and Histopathology. Cardiovascular: MI/ Arrhythmias, Angina, Heart failure, Hypertension, CNS: Memory/cognition,…

Product Development for NCE and Biopharmaceuticals

5 years ago

Pre-clinical lead optimization is the early assessment of a compound’s development potential. Lead optimization reduces the risks associated with selecting…